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Moloney et al., 2021)

The renal domain of SLICC/ACR (Systemic Lupus International Collaborative Clinics/American College of Rheumatology) Damage Index (SDI) is associated with early mortality in SLE

Therefore, the major endogenous source of intracellular reactive species in RBCs is the slow auto-oxidation of haemoglobin, which produces non-functional methaemoglobin and superoxide radicals that rapidly dismutase to form hydrogen peroxide (H 2 O 2 ) (Fujii et al., 2021)

The growth response to GH treatment in children with GH deficiency is not different between those who do or do not normalize their IGF-I levels

Virtually all organisms possess scavenging enzymesa mixture of catalases and peroxidasesto keep intracellular H 2 O 2 scant, but concentrations can still become hazardous if the rate of influx is high enough