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While the etiology of PD remains incompletely understood, a combination of genetic predispositions and environmental exposures has been implicated

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Pinho, A

In addition, we show that heterologous production of pelargonidin-3- O -glucoside ( 14 ) and delphinidin-3- O -glucoside ( 15 ) can be similarly enhanced

In addition, this deletion completely cancels the increase in ROS production caused by the gmhA deletion , while all other mutations in the genes that regulate the metabolism of cysteine and glutathione, as well as a violation of cystine transport, lead to an even greater increase in the level of ROS in cells with a gmhA deletion