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It might be a sign of biliary tree obstruction See item 4 for more 8

doi: 10.1016/j.tplants.2016.08.002 18 Di MeoSReedTTVendittiPVictorVM

Furthermore, changes in certain biochemical markers are recognized as important indicators for the early identification of PPROM

Cell Mol Biol Lett 27(1):128

Statistical analysis was performed using two-way analysis of variance (ANOVA) for the cytotoxicity assay and one-way ANOVA for the rest of experiments