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Table 1 summarizes the recent safety characteristics of the three major DPP1 inhibitors (Zhong et al., 2025

References Sikiric P, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, et al

The kidney is highly abundant in mitochondria and therefore represents a vulnerable site to ROS-induced damage

The activation of JNK results in the phosphorylation and activation of the JUN transcription factor

The starting conformations were obtained by manually binding GS(H) to a snapshot of the MD simulation of TRaQ-G and the crystal structure of MeTRaQ-G, respectively
