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Some studies suggest AOD-9604 may support collagen synthesis in chondrocytes and reduce joint inflammation, which could be a secondary benefit for anyone carrying excess weight that stresses their joints

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Strong evidence, from decades of treating individuals with inborn errors of B 12 metabolism, supports the safety of parenteral, lifelong, even high dose hydroxocobalamin, sometimes even at very high doses.6768 Long term epidemiological studies also indicate that treatment with pharmacological B 12 doses and the corresponding increase in serum B 12 do not increase mortality.69 Data on the safety of cyanocobalamin, when administered with high frequency (ie, one to two times a week) for a longer period of time, are lacking

A provider who offers medical weight loss can help you track these markers and adjust your treatment plan based on your progress

If any of that rings true for you, sitting down with a provider is a sensible move