mitochondrial damage glutathione and mitochondria Frontiers | Glutathione and mitochondria

It has been shown that KD may have anti-tumor potential for several cancer types, including colorectal, brain, breast, and pancreatic cancer (39, 81, 82)

The pentose phosphate pathway is the only source of NADPH in red blood cells, and the major function of NADPH in this cell type is to maintain the tripeptide glutathione (GSH) in its reduced state, which is needed to detoxify reactive oxygen species (Figure 3)

These non-hypoxic activation mechanisms are particularly relevant in inflammatory conditions such as osteomyelitis (Figure 2)

Ha oxidldik, a glutationot vissza lehet cskkenteni glutation-reduktzzal, NADPH elektrondonor alkalmazsval

10.1055/s-2008-1068757 Semin