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273 Indeed, the relationship between increased tight junction-dependent paracellular permeability and gastrointestinal diseases is shown in Figure 5

The UniProt database with human entries (October 2017) was used for the database searches

The type 2 nuclear receptors of most importance to drug metabolism and drug therapy include the pregnane X receptor (PXR), constitutive androstane receptor (CAR), and the peroxisome proliferator activated receptors (PPARs)

Changes in tryptophan metabolism within the kynurenine pathway were correlated with increased IL-6 in COVID-19 patients (Thomas et al

Ansari F, Bahadori A, Samakkhah SA, et al (2023) Probiotic lactic acid bacteria
