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This distinction fundamentally shapes its pharmacokinetic profile, granting it properties (oral bioavailability, protease resistance, BBB penetration) that most neuropeptides lack

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Nanoparticles have also been developed to improve wound healing, mainly via ROS scavenging, anti-inflammatory and antibacterial effects, and applied to several in vitro and in vivo models 180,181,182,183,184 , as well as other molecules 185,186,187,188

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