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J Biol Chem 281: 87658772 [DOI] [PubMed] [Google Scholar] Maroun C.R., Naujokas M.A., Park M

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The following is aggregated from user reports and extrapolated from preclinical data

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Babu H, Ramirez-Rodriguez G, Fabel K, Bischofberger J, Kempermann G (2009) Synaptic network activity induces neuronal differentiation of adult hippocampal precursor cells through BDNF signaling

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Notably, MOTS-c treatment enabled old mice to outperform untreated middle-aged mice, suggesting a more pervasive physical reprogramming rather than just rejuvenation

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