labial melanotic freckle macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Happy Wednesday! , In this

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A mosaic pattern is commonly observed with COX-negative fibers appearing blue, among the normal COX-positive fibers which appear brown (Fig

Tetrahexyldecyl Ascorbate: This oil-soluble form of vitamin C is stable and easily absorbed by the skin, providing sun protection, brightening effects, and wrinkle reduction

If the skin begins producing more melanin than usual, it can lead to hyperpigmentation

The diagnosis is made from the architectural pattern of the lesion (asymmetrical, poorly circumscribed and with variable nests of melanocytes) and cytomorphology (spindled, pagetoid, small and large round-shaped, polygonal, multinucleate and/or with dendritic characteristics)