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K Scanlon, PhD, L Grummer-Strawn, PhD, L Kettel Khan, PhD, Div of Nutrition and Physical Activity, National Center for Chronic Disease Prevention and Health Promotion

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Some studies have reported increased concentrations of opioid peptides (Jarmoowska et al
Alcohol and Folate, B6, B12, and SAMe Depletion: Methylation Impairment and Elevated Disease Risk Alcohol has a profound impact on methylation-related nutrients, including folate, vitamin B6, vitamin B12, and S-adenosylmethionine (SAMe)

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