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PMCID: PMC8401986

Additionally, preclinical and early clinical findings point to an involvement in thyroid cancers and nodules

( 10.1016/j.eururo.2018.12.022) [DOI] [PubMed] [Google Scholar] Poljsak B.2011

PubMed Pairs well with Niacinamide Centella Asiatica Extract Azelaic Acid Glycolic Acid L-Carnitine Tranexamic Acid Licochalcone A Sunscreen agents (mineral and chemical) Avoid combining with Benzoyl Peroxide (may be less stable in combination) Vitamin C (L-Ascorbic Acid, pH-dependent interaction) Strong Retinoids (increased irritation risk) Aluminium Chloride (may increase keratolytic effect excessively) INGREDIENT RETINOID, VITAMIN A DERIVATIVE Retinol also known as Vitamin A, Retinyl Alcohol Function May help support skin cell turnover, collagen synthesis, and reduction of fine lines and wrinkles through vitamin A receptor activation How it works Retinol undergoes metabolic conversion to retinaldehyde and retinoic acid, which bind to nuclear retinoid receptors (RAR and RXR) in keratinocytes and fibroblasts

Alcohol can lower B-vitamin levels and reduce benefits, so limit intake