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10.1016/j.brainres.2010.03.090 Brain Res

There is evidence of neuroendocrine dysfunction, mitochondrial and oxidative stress, inflammation, and loss of neuroprotective factors

In particular, fatigue generates a series of inflammatory responses in the body, changing the levels of IL-1, IL-2, IL-6, and TNF-, which are the key pro-inflammatory cytokines involved in the initiation of the anti-inflammatory response to injury

Restoration of deficiency Prophylactic or therapeutic carnitine supplementation can increase plasma levels swiftly

Necessity of SMA Newborn Screening 7.1