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Whilst vitamin B12 toxicity is exceptionally rare due to its water-soluble nature, very high levelsparticularly from mega-dose supplements or frequent injectionshave been associated with certain adverse effects, most notably skin reactions

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By increasing blood supply to a wounded area, BPC-157 helps to increase the penetration of immune system cells that fight off infection while simultaneously carrying away debris and damaged tissue that could foster microbial growth

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et al.: Methylmalonate excretion in a patient with pernicious anemia (1963) The New England journal of medicine | DOI: 10.1056/NEJM196301172680309