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mRNA was purified by NEBNext Poly(A) mRNA Magnetic Isolation Module (NEB, E7490S) from Turbo-DNase-treated total RNA

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In order to confirm a diagnosis of VKDB one must measure for the level of the specific vitamin K-dependent factors (prothrombin, VII, IX, X)

142 The action of ASP was also evaluated in vitro, providing novel evidence for its growth inhibitory effect, antiproliferative, proapoptotic, and antifibrotic actions on cultured leiomyoma cells in the absence of comparable effects on cultured normal myometrial cells