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Jorgensen L, Jenssen T, Joakimsen O, et al

10.1016/j.neuron.2012.03.032 58

doi: 10.1152/ajpcell.00043.2009 43 TaylorWEBhasinSArtazaJByhowerFAzamMWillardDHet al

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Subsequent studies reveal that RIPK1 and RIPK3 (receptor interacting serine/threonine kinase 3) are key upstream kinases that initiate necroptosis through the phosphorylation of executor protein MLKL (mixed lineage kinase domain like pseudokinase) by multiple regulators [112]
