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These alterations in metabolic pathways are in accordance with our results as we detected an increased expression of FAO components and decreased glycolytic enzyme expression in CMV-specific CD8 + T cells of noncontrollers

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For initial analysis of glucose-related metabolism we cultured virus-specific T cells ex vivo in the presence of the fluorescent glucose-analogue 2-NBDG, which serves as a surrogate for glucose uptake (22)

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