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Primarily, it enhances the immune system, aiding in bolstering the body's defense mechanisms against pathogens and supporting overall immune health

Therefore, attention has been focused on natural antioxidants mainly from plant sources [33, 34]

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An example of an NO prodrug is O 2 -(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K), devised by Keefer et al from the National Cancer Institute