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Enzymatic activation triggers two main modifications at synapses: changes in -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) number and activity (Hayashi et al., 2000

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Both angiogenesis and vasculogenesis have been shown to play roles in progression of diseases including cancer, ischemia, and arterial stiffening (63, 64)

Ibuprofen targets neuronal pentraxins expresion and improves cognitive function in mouse model of AlCl3-induced neurotoxicity
Acute toxicity in animal models is described as low for all three peptides individually, but coadministration data are sparse
