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BPC-157 (Body Protection Compound-157, CAS 137525-51-0, ~1419 g/mol) is a synthetic pentadecapeptide studied in vitro and in preclinical models for interactions with nitric oxide signalling, VEGF and EGF growth-factor pathways, and cytoprotection

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TB-500 is a synthetic fragment derived from Thymosin Beta-4, a protein involved in regulating actin, the structural protein central to cell movement

The hypothalamus produces a hormone called the Gonadotrophin Releasing Hormone which stimulates the pituitary gland to produce FSH and LH

CEPs are comprised of subchondral bone and hyaline cartilage and are the linkage points between the vertebral bone and the AF (Sivakamasundari and Lufkin, 2012)