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52% increase in intracellular glutathione* 400% increase in natural killer cell function* 25% reduction in oxidative stress* 2-year shelf life at room temperature No refrigeration necessary The proof is in the peer-reviewed, published clinical research and third-party testing An in vivo study using Tri-Fortify as the sole nutritional intervention was conducted to assess changes in intracellular glutathione absorption, natural killer cell function, and oxidative stress markers

On the upside, it can penetrate the skin better (though 10kDa still counts as big!) and might be able to moisturize the deeper layers of the skin where normal HA cannot get

The following sections provide a brief review of these concepts