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Copper and OxS and mitochondrial dysfunction Excessive intracellular copper levels increase the generation of reactive oxygen species (ROS) and trigger OxS through multiple mechanisms

In this study of 545 patients with type 2 diabetes, TIR showed a strong negative correlation with HbA1c, indicating its potential as both a short-term and long-term diabetes management marker
Methylglyoxal metabolism in trypanosomes and leishmania

In the ELISA, control samples were analyzed each time to check the variation from plate to plate on different days of analysis