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the cut-off was set is 66 ng/mL 12 weeks from the start of treatment with 50,000 IU of vitamin D per week

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In fact, phenomena such as insufficient stability in the stomach, reduced solubility, and hepatic degradation result in a bioavailability of approximately 30% and a short half-life of ALA, whereas intravenous injection of ALA in other models achieves higher bioavailability