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2,3-DPG could be hydrolysed by phosphoglycerate phosphatase to 3-phosphoglycerate, releasing a Pi (Reference Rapoport and Luebering47)

A recent systematic review in 2024 detected that curcumin was found to upregulate several tumor-suppressive microRNAs, including miR-497, miR-200c, miR-200b, miR-409-3p, miR-34, miR-126, miR-145, miR-206, miR-491, miR-141, miR-429, miR-101, and miR-15a
10.1016/j.jep.2004.04.021 235
[DOI] [PMC free article] [PubMed] [Google Scholar] 307.Caldwell, C

One such approach involves increasing the expression of EAATs to improve glutamate metabolism, thereby supporting neuronal survival