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Consequently, they have emerged as promising candidates for a new generation of tumor imaging and therapeutic agents of various CD38-expressing malignancies [85, 88]
In parallel, radiolabeling of daratumumab with [ 89 Zr]Zr-oxalate has been developed as an alternative imaging approach [101]
Reticulocytosis (increased production of immature red blood cells) typically begins by day 3-4 of starting treatment, indicating active bone marrow recovery
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However, if any particulate matter remains undissolved or the solution remains cloudy, the vial should be discarded for safety
