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Safety and Clinical Considerations Gastrointestinal adverse effects The most common adverse effects of incretin-based therapies are gastrointestinal, including nausea, vomiting, diarrhea, constipation, dyspepsia, and abdominal discomfort

Pulsatile release means that the hormone is secreted in bursts or pulses rather than a continuous, steady flow

According to literature references, 86,87 the isomers of phenylenediamine have been widely applied to successfully synthesize CDs with long emission wavelengths which can be better tracked in biological tissues

doi: 10.1177/2235042X19853484

These characteristics have led to the use of sCD14 as a surrogate marker for bacterial translocation and gut barrier dysfunction, and even as a potential target for developing monoclonal antibodies to treat sepsis [256, 257]