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By 104 weeks, approximately 77% of SELECT patients on dose were receiving the target semaglutide 2.4 mg weekly dose, which is lower than the corresponding proportion of patients in STEP 1 (89.6% were receiving the target dose at week 68) 14,21

In humans, high selenium supplementation (which may increase the expression of GPx1, as well as that of other selenoproteins) was associated with increased risk of type 2 diabetes [103, 104]

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Fewer branches, shorter total branch lengths, and a higher somatic-to-total cell size ratio are indicative of microglial activation