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Cell 138 , 314327 (2009)

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Autophagy and regulation of lipid metabolism

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However, Humans are poor subjects for these studies because of heterogeneous genetic backgrounds, low reproductive rate, generation times far too important for experimental studies, wide variations in gene expression, subject to strong environmental variations and experimentations on humans are unethical

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Riggio O, Merli M, Cantafora A, Di Biase A, Lalloni L, Leonetti F, Miazzo P, Rinaldi V, Rossi-Fanelli F, Tamburrano G, et al

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