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Molecular dynamics simulations Molecular dynamics simulations have been performed using the AMBER ff19SB force field 57 and the solvent molecules were represented as OPC water molecules 58

Given the central role of NMDA receptors in tinnitus-related excitotoxicity and synaptic plasticity, NMDA receptor antagonists have been investigated as a rationally based therapeutic strategy, repurposing knowledge from neurodegenerative conditions like AD where drugs such as memantine are used (Rafe et al., 2024)

Diosgenin down-regulates NF-kappaB p65/p50 and p38MAPK pathways and attenuates acute lung injury induced by lipopolysaccharide in mice

UV exposure will undo every effort within weeks

Direct intravenous B12 for rapid energy, neurological support, and cognitive clarity