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Based on these contradictory events, whether differences in the rate of lipid peroxide production affect the role of lipid peroxidation in inducing pyroptosis remains unresolved

N Z Med J 128:6164 Davies SE, Iles RA, Stacey TE, de Sousa C, Chalmers RA (1991) Carnitine therapy and metabolism in the disorders of propionyl-CoA metabolism studied using 1 H-NMR spectroscopy

It is also why side effects can appear quickly

doi: 10.1016/S1470-2045(13)70088-3

However, while the AF3 prediction of NS3 binding to this region is compelling and supports the eCLIP data, previous studies showed no or only limited impact of mutations in SL3.1 and SL3.3, respectively, on RNA replication 69 , suggesting rather auxiliary than essential functions of this interaction