glutathione synthetase reference value system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Measurement of Glutathione as a

Tavares-Valente D, Cannone S, Greco MR, Carvalho TMA, Baltazar F, Queiros O, et al

ROS are short-lived molecules produced by normal cellular metabolism and aid in a multitude of physiological and pathological processes

As becomes evident above, GSH S-conjugates are related to the: (a) diseases state, (b) exposure of the body to aerial, nutritional and other chemicals (representing the exposome of the body) and (c) drugs, constituting a major part of pharmacometabolomics (Figure 3)

The possible function of SULTR1;2 (Zhang et al., 2014) as a sulfate sensor is intriguing, particularly as the Chlamydomonas regulator of S-starvation response, SAC1, is similar to SULTR of the SLC13 group (Davies et al., 1996

This is the first study to demonstrate the formation of the NFT radical anion by EPR spectroscopy in live HepG2 cells treated with NFT (Fig