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By blocking NNMT activity, 5-Amino-1MQ raises intracellular SAM levels and simultaneously elevates NAD+ precursor availability creating conditions that research has associated with reduced fat cell differentiation and improved metabolic signaling

doi: 10.1111/j.1460-9568.1993.tb00221.x

doi: 10.2105/AJPH.2015.302773

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