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One systematic review (Inchingolo et al., 2020) looking at natural antioxidants in OSF included curcumin trials and noted significant improvement in burning sensation and mouth opening in curcumin groups compared to baseline ( 5.6 Anticaries/oral hygiene studies While not as many RCTs exist for caries, the antiplaque efficacy of curcumin mouthwash has strong evidence (multiple trials vs

[PubMed Central] Sloen: N-acetyl-L-cystein (49,4 %)
doi: 10.3390/nu8080513 85
By wrapping the glutathione in a phospholipid shell, we allow it to be absorbed more efficiently at the cellular level