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Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome (in Eng)

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Public Health 6 , 104 (2018)

Simultaneously, their application fields may further expand to COPD, cystic fibrosis, and other neutrophil-mediated inflammatory diseases

Rather than indiscriminately blocking macrophage activity (which would impair the early inflammatory debridement phase of wound healing), GHK-Cu research documents a shift in macrophage phenotype from pro-inflammatory M1 toward the anti-inflammatory, pro-healing M2 profile at later stages of the inflammatory response