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Interference with the NF-B signaling pathway sensitizes hepatocytes to TNF-induced death

The results indicated an increase in oxidative stress levels and a reduction in antioxidant enzyme levels in the rabbits that were treated with the NPs [51]

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Long-term dietary restriction or PHGDH inhibition may lead to neurological disorders, such as cognitive impairment and abnormal motor coordination (123, 133), as well as hepatic dysfunction (134)

However, ingestion of foodstuffs rich in monosodium glutamate can result in the outbreak of several health disorders such as neurotoxicity, hepatotoxicity, obesity and diabetes