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UTIs, presumably due to reduced immune cell function

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A study in the Journal of Clinical Biochemistry says, Vitamin B12 deficiency can cause big problems with nerves and blood. Vitamin B12 is key for making DNA, fatty acids, and energy. Source: Journal of Clinical Biochemistry Common Signs of Deficiency A Vitamin B12 shortage can show in many ways, like: Fatigue and weakness Numbness or tingling in hands and feet Difficulty walking Mood changes, such as depression Spotting these signs early is key for quick action

When's the Right Time to Say Goodbye

Many community references include 2-4 week off-periods between cycles to allow fresh evaluation, although the rationale is community-derived rather than trial-validated