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Andrographolide antagonizes TNF-alpha-induced IL-8 via inhibition of NADPH oxidase/ROS/NF-kappaB and Src/MAPKs/AP-1 axis in human colorectal cancer HCT116 cells

Cystine uptake assay Cystine uptake was measured as described previously 92

Non-stimulated control mitochondria did not undergo measurable changes in morphology, further supporting that these changes were due to spatially restricted ROS generation through KR photostimulation

Despite the continuous improvement of international diagnostic and treatment guidelines and IS management systems, the clinical application of rtPA still faces significant limitations

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