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(XLSX 181 KB) 12866_2013_2011_MOESM5_ESM.pptx (download PPTX Additional file 5: Figure S2: Two Venn diagrams revealing the partially overlapping pattern of gene expression between day 2 and day 8 spherules in this study and day 4 spherules in the Whiston et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 146.Sandstead HH

These observations indicate that detoxification capacity is not static, but rather represents a dynamic, inducible adaptive response

De novo synthesis occurs in a two-step reaction catalyzed by two separate enzymes, glutamine-cysteine ligase (GCL) and glutathione synthase (GS), as shown in Figure 1