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Valproate overdose: a comparative cohort study of self-poisonings

Most first-opinion clinicians preferred treatment is oral medical treatment (66%), with surgical thyroidectomy (28%) and radioiodine (5.5%) used less frequently 2

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In this Review, we describe the evidence for abnormalities in energy metabolism and mitochondrial function in migraine, with a focus on clinical data (including neuroimaging, biochemical, genetic and therapeutic studies), and consider the relationship of these abnormalities with the abnormal sensory processing and cerebral hyper-responsivity observed in migraine