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When searching for potential biomarkers of disease status, it was determined that individuals with konzo did have a higher incidence of albumin carbamoylation, a post-translational modification likely induced by increased exposure to a toxic byproduct of linamarin degradation, cyanate 29

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The c-jun NH2-terminal kinases (JNKs) are recognized as critical regulators of apoptosis, initiated in reaction to cellular damage

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For most beginners, this means using retinol just once or twice per week for the first two to three weeks