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These enzymes, activated notably by UV radiation and oxidative stress, are responsible for the degradation of collagen and other constituents of the dermal matrix

Reprogramming of macrophages employing gene regulatory and metabolic network models

Surgical resection is the sole potentially curative option for CCA (Blechacz, 2017), but a study of patients with iCCA in the US National Cancer Database found only 21.9% underwent surgical resection (Wu et al., 2019)

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