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In vivo magnetic resonance spectroscopy (H-MRS) have reveals age-dependent reductions in GSH in metabolically active brain regions, including the hippocampus, posterior cingulate cortex, and frontal cortex [17, 18, 21], regions that are also among the earliest and most severely affected in AD [18, 21]

Initial injections may be weekly or monthly to rapidly raise levels, followed by maintenance injections as needed

These abnormalities extend to the hypothalamicpituitaryadrenal (HPA) axis, which plays an essential role in the complex pathophysiology of fibromyalgia [159]

The maximum decline of 3.25 folds in catalase activity was observed for 20,000 ppm iron overload ( Table 3 and Figure 3 )

HO-1 expression is regulated and repressed by the transcription factor Bach1 (BTB and CNC homology 1) and activated through the regulation of Nrf2 (Dun et al., 2021)
