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We next hypothesised that NADP oxidation during hypoxia may be due to NADPH consumption by the antioxidant machinery which is not matched by the rate of resupply due to limitations in flux through central metabolism

Jowett, J

Texas Association of Otolaryngology Annual Meeting

By directly scavenging these toxic byproducts, S-A-GSH takes the immense pressure off the struggling mitochondrial enzymes
