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A study found that the expression levels of SOD3 in the skin tissues of aging mice and humans were significantly lower than those in young skin tissues, while the expression levels of SOD1 and SOD2 remained unchanged during the aging process [52]

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doi: 10.3389/fmicb.2025.1641185 Received 06 June 2025 Accepted 29 August 2025 Published 02 October 2025 Volume 16 - 2025 Edited by Jianan Zhao, Temple University, United States Reviewed by Faheem Ahmed Khan, National Research and Innovation Agency (BRIN), Indonesia Shreya Madhav Nuguri, The Ohio State University, United States Updates Copyright 2025 Durn-Gonzlez, Ramrez-Tejero, Prez-Snchez, Morales-Torres, Gmez-Morano, Daz-Lpez, Martnez-Lara and Cotn