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Physiological melanin hyperpigmentation does not require treatment, but if for cosmetic reasons it has to be removed, laser or cryotherapy or surgical excision are often successful

Yan Y, Liu X-Y, Lu A, Wang X-Y, Jiang L-X, Wang J-C

Ripening and flavor production

However, the difficulty with the Clarks classification system lies in the subjective nature in the determination of the depth of invasion

Therefore, early intervention is paramount for CAC deficiency
