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When histamine remains elevated, it contributes to NMDA receptor overactivity , neuroinflammation, and impaired serotonin functionnot necessarily low serotonin production, but poor serotonin signaling and utilization
doi: 10.1016/j.amjmed.2014.10.014 218
Interestingly, the reduction in hydrogen in the small intestine was similar in both groups
b.i.d., twice daily
Am J Physiol Endocrinol Metab (2014) 307:E84755
