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Green tea supplementation adequately recovered catalase activity in ISO-administered rats ( p 0.01) (Fig

This results in formation of the -klotho-FGF4-FGF19 complex, which inhibits CYP7A1 expression and bile acid synthesis

Another group generated isogenic hiPSC lines with engineered mutations in exon 2 and 8 of the DISC1 , leading to loss of long DISC1 isoforms and affecting NPC proliferation, baseline WNT signaling and the expression of NPC fate markers such as FOXG1 and TBR2 [143]

After centrifugation (250 x g , 5 min, 4C), cells were resuspended in with Hepes-buffered saline (HBS, 14 mM Hepes, 0.9% NaCl) and analyzed in duplicate by flow cytometry (FACSCanto II, BD Biosciences, San Jose, CA, USA)