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Nature 627 , 340346 (2024)

Rotate injection sites to prevent irritation

Weeks 5-6: Continued improvement for most conditions

A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al

However, taking into consideration that Vit B12 deficiency can induce the elevation of Hcy levels, it seems plausible to consider the non-motor aspects related to Hcy (Shipton and Thachil 2015)