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Vitamin B12 is a water-soluble vitamin and is essential for the proper function of the brain, nervous system, and the formation of red blood cells

S., Brcic, L., Sever, M., Klicek, R., Radic, B., Drmic, D., Ilic, S., Kolenc, D., Aralica, G., Safic, H., Suran, J., Barisic, I., Dzidic, S., Vrcic, H., & Sebecic, B

This question is especially important to optimize hormone therapy for women who might undergo bilateral oophorectomy prior to the age of natural menopause and require menopausal hormone therapy to reduce the risk of multimorbidity of aging.50, 51, 52 Our group has taken a candidate gene approach to begin to evaluate how genetic variants in enzymes involved in estrogen metabolism might be related with response to estrogen therapies