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Methods: The researchers from Florida Atlantic University, had test subjects randomized to placebo or glycine propionyl-l-carnitine supplementation

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Genetic polymorphisms, low-grade inflammation, poor diet, dysbiosis, and chronic disease, including diabetes and cardiovascular disease, may increase the conversion of TMA to TMAO

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7 Discussion Current MASLD management primarily relies on lifestyle interventions, including weight reduction, dietary modification, and physical activity ( This review has systematically summarized evidence suggesting that L-carnitine exerts multi-targeted actions against MASLD pathogenesis by promoting lipid metabolism, improving insulin sensitivity, stabilizing hepatocyte function, and inhibiting inflammatory and fibrotic signaling pathways